ADIPOQ anticorps (AA 145-226)

N° du produit ABIN6936364

Cet anticorps anti-ADIPOQ est un anticorps Souris Monoclonal détectant ADIPOQ dans WB et IHC (f). Adapté pour Humain.

Aperçu rapide pour ADIPOQ anticorps (AA 145-226) (ABIN6936364)

Antigène: ADIPOQ (Adiponectin (ADIPOQ))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ADIPOQ est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Clone: ADPN-1370

Détail du produit anti-ADIPOQ anticorps

Épitope: AA 145-226

Specificité: This MAb reacts with adiponectin, an adipocytokine. Adipocytokines are hormones produced in adipose tissue. Adiponectin is abundantly present in plasma and has insulin like effect on glucose levels in the blood. Plasma adiponectin levels are low in insulin resistant patients who are obese, have diabetes mellitus type 2 or HIV-lipodystrophy. In women adiponectin levels tend to be higher than in men, which may be due to androgens suppressing adiponectin levels. Furthermore adiponectin and leptin are both indicated in regulating body weight through direct action on the hypothalamus, influencing appetite. Obese people have low adiponectin levels while levels in anorexia patients are high. Adiponectin acts as ligand for various receptors, two of which have been identified, one probably involved in carbohydrate assimilation, the other in tuning the rate of metabolism.

Réactivité croisée (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogène: Recombinant human Adiponectin protein fragment (around aa 145-226) (exact sequence is proprietary)

Isotype: IgG2b kappa

Information d'application

Indications d'application:

Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Kidney.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Date de péremption: 24 months

Détails sur ADIPOQ

Antigène: ADIPOQ (Adiponectin (ADIPOQ))

Autre désignation: ADIPOQ

Sujet: Adiponectin, Adipocyte complement-related 30 kDa protein (ACRP30), Adipocyte-specific secretory protein, Adiponectin, C1Q and collagen domain containing (ACDC), ADIPOQ, Adipose most abundant gene transcript 1 protein, Adipose specific collagen like factor, ADIPQTL1, ADPN, APM-1, Gelatin-binding protein 28 (GBP28),Adiponectin (Marker of Obesity)
Cellular localisation: Cytoplasmic & Cell Surface

Poids moléculaire: 26-30kDa

ID gène: 9370, 80485

UniProt: Q15848